SCHEMBL29664280

SCHEMBL29664280

OB(O)c1ccccc1-c1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
PTGS2 P35354 2/20 0.47
CYP1A2 P05177 2/20 0.44
ENPP2 Q13822 2/20 0.43
PTGS1 P23219 1/20 0.43
ORAI1 Q96D31 1/20 0.42
ORAI2 Q96SN7 1/20 0.42
ORAI3 Q9BRQ5 1/20 0.42
TRPV6 Q9H1D0 1/20 0.42
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
FGFR1 P11362 1/20 0.38
SRC P12931 1/20 0.38
FGFR2 P21802 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1742339 1.00 SLC6A4 (0.47) SLC6A4SLC6A3PTGS2CYP1A2ENPP2
SCHEMBL29825386 0.83 MGLL (0.54) PTGS2ENPP2HSD17B10HPGDALDH1A1
SCHEMBL4145743 0.83 MGLL (0.54) PTGS2ENPP2HSD17B10HPGDALDH1A1
SCHEMBL21933 0.82 ALDH1A1 (0.48) PTGS2ENPP2HSD17B10HPGDALDH1A1
SCHEMBL29838597 0.82 ALDH1A1 (0.48) PTGS2ENPP2HSD17B10HPGDALDH1A1
Benzene SCHEMBL28163950 0.82 ALDH1A1 (0.48) PTGS2ENPP2HSD17B10HPGDALDH1A1
SCHEMBL1853561 0.81 CA2 (0.44) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL31364709 0.81 ABL1 (0.52) ENPP2HSD17B10HPGDALDH1A1MEN1
Methyl Alcohol SCHEMBL28631854 0.80 ALDH1A1 (0.46) PTGS2ENPP2HSD17B10HPGDALDH1A1
Water SCHEMBL29954878 0.80 ALDH1A1 (0.46) PTGS2ENPP2HSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960001-A Organic compound, and electronic element and electronic device comprising same 陕西莱特光电材料股份有限公司 2023-04-14 CN disclosed
CN-114728924-A Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2022-07-08 CN disclosed
WO-2022131546-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2022-06-23 WO disclosed