SCHEMBL29664384

SCHEMBL29664384

O=C(O)c1c(O)ccc2c1OCCO2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
HTT P42858 2/20 0.45
HSD17B10 Q99714 2/20 0.45
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ALOX5 P09917 1/20 0.41
CNR2 P34972 1/20 0.40
RAB9A P51151 2/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
ALOX15 P16050 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27253938 1.00 KDM4E (0.45) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL29054677 0.80 KDM4E (0.44) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL15569955 0.80 KDM4E (0.44) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL30507841 0.80 KDM4E (0.44) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL11270162 0.80 DPP4 (0.46) KDM4EALDH1A1HPGDHTTHSD17B10
Hydrochloric Acid SCHEMBL11259230 0.79 KDM4E (0.43) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL22876711 0.76 ALOX5 (0.40) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL27253971 0.76 PARP1 (0.45) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL11262989 0.75 TXNRD1 (0.46) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL25958133 0.75 CA12 (0.36) KDM4EALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092029-A1 LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE SCRIPPS RESEARCH INST (US) 2026-04-02 US claimed
EP-4584236-A1 LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE The Scripps Research Institute (US) 2025-07-16 EP claimed
WO-2024054881-A1 LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE THE SCRIPPS RESEARCH INSTITUTE (US) 2024-03-14 WO claimed
US-20260092029-A1 LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE SCRIPPS RESEARCH INST (US) 2026-04-02 US disclosed
EP-4584236-A1 LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE The Scripps Research Institute (US) 2025-07-16 EP disclosed
US-20250188046-A1 ULTRAFAST FLOW SYNTHESIS OF FUNCTIONALIZED SULFONYL FLUORIDES AND SUBSEQUENT SUFEX CONNECTIONS VIA LITHIATED CHEMISTRY POSTECH Research and Business Development Foundation (KR) 2025-06-12 US disclosed
US-20240308931-A1 LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS THE SCRIPPS RESEARCH INSTITUTE 2024-09-19 US disclosed
EP-4370490-A1 LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS The Scripps Research Institute (US) 2024-05-22 EP disclosed
WO-2024054881-A1 LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE THE SCRIPPS RESEARCH INSTITUTE (US) 2024-03-14 WO disclosed
US-20240059656-A1 A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN THE SCRIPPS RESEARCH INSTITUTE 2024-02-22 US disclosed
CN-117209381-A Carboxylic acid compound containing carbon ring and heterocycle and synthesis method thereof 四川大学 2023-12-12 CN disclosed
WO-2023287964-A1 LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS THE SCRIPPS RESEARCH INSTITUTE (US) 2023-01-19 WO disclosed
CN-115073383-A Synthetic method of aryl acetic acid compound 四川大学 2022-09-20 CN disclosed
WO-2022125736-A1 A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN THE SCRIPPS RESEARCH INSTITUTE (US) 2022-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308931-A1 LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS PPARD, PPARA, PDCD1LG2 KDM4E 3952/4885ALDH1A1 144/4885HPGD 255/4885
US-20260092029-A1 LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE CYP2B6, CYP2A6, CYP1A1 KDM4E 2985/4885ALDH1A1 137/4885HPGD 110/4885
US-20250188046-A1 ULTRAFAST FLOW SYNTHESIS OF FUNCTIONALIZED SULFONYL FLUORIDES AND SUBSEQUENT SUFEX CONNECTIONS VIA LITHIATED CHEMISTRY FGFR4, STS, FGFR1 KDM4E 2533/4885ALDH1A1 1626/4885HPGD 4811/4885
US-20240059656-A1 A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN PAH, OGDH, DOHH KDM4E 965/4885ALDH1A1 326/4885HPGD 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.