Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018903 | 1.00 | THRB (0.43) | THRBJMJD6NPC1LMNARAB9A | |
| SCHEMBL20399682 | 0.87 | JMJD6 (0.43) | JMJD6NPC1LMNARAB9ACYP2C9 | |
| SCHEMBL30697102 | 0.87 | JMJD6 (0.43) | JMJD6NPC1LMNARAB9ACYP2C9 | |
| SCHEMBL15968597 | 0.85 | CA12 (0.46) | JMJD6NPC1LMNARAB9ACYP2C9 | |
| SCHEMBL18394836 | 0.84 | NPC1 (0.49) | NPC1LMNARAB9AAGBL2CYP2C9 | |
| SCHEMBL17362538 | 0.84 | TARBP2 (0.42) | JMJD6NPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL7684716 | 0.84 | S1PR1 (0.49) | JMJD6NPC1LMNARAB9ACYP2C9 | |
| SCHEMBL25780807 | 0.83 | GABRA1 (0.43) | JMJD6NPC1LMNARAB9AAGBL2 | |
| SCHEMBL29050073 | 0.81 | KDM4E (0.41) | THRBNPC1LMNARAB9AAGBL2 | |
| SCHEMBL30405953 | 0.81 | KDM4E (0.41) | THRBNPC1LMNARAB9AAGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119454711-A | Methods, compositions and crystalline forms of substituted pyridone-pyridinyl compounds | 阿克拉瑞斯治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119053588-A | P38 alpha-MK 2 inhibitor compound, pharmaceutical composition and application thereof | 长春金赛药业有限责任公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-115484952-B | Methods, compositions and crystalline forms of substituted pyridone-pyridinyl compounds | 阿克拉瑞斯治疗股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-116685322-A | Method for synthesizing substituted pyridone-pyridyl compounds | 阿克拉瑞斯治疗股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-115484952-A | Methods, compositions, and crystalline forms of substituted pyridone-pyridyl compounds | 阿克拉瑞斯治疗股份有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-108200760-B | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |