SCHEMBL29664672

SCHEMBL29664672

Fc1ccc(-c2ccc(Cl)nn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.52
NPC1 O15118 7/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 6/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPT P10636 3/20 0.40
HPGD P15428 3/20 0.40
HTT P42858 2/20 0.40
PKM P14618 1/20 0.40
MAOB P27338 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
ALOX5 P09917 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1686039 1.00 RAB9A (0.52) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL256008 0.82 HSD11B1 (0.48) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL1951455 0.81 MEN1 (0.35) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL928222 0.78 METAP2 (0.39) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL3152568 0.78 KDM4E (0.42) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL13458074 0.78 SMN1; SMN2 (0.47) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL2314305 0.78 MAPT (0.45) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL930699 0.78 CASP1 (0.45) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL30367878 0.78 CASP1 (0.49) ALDH1A1HPGDMAOBALOX5
SCHEMBL1741626 0.78 CASP1 (0.49) ALDH1A1HPGDMAOBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111386118-B Combination pharmaceutical agents as RSV inhibitors 英安塔制药有限公司 2023-05-09 CN disclosed
CN-108200760-B Benzodiazepine derivatives as RSV inhibitors 英安塔制药有限公司 2022-04-01 CN disclosed