Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078295 | 1.00 | PLAU (0.51) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL29489119 | 0.80 | CYP2A6 (0.54) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL8156941 | 0.80 | EGFR (0.48) | APPMEN1NPC1KMT2ACYP2A6 | |
| SCHEMBL1344485 | 0.80 | CYP2A6 (0.54) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL360149 | 0.78 | LOXL2 (0.54) | APPMEN1RAB9AKMT2AABCB1 | |
| SCHEMBL7344351 | 0.78 | PLAU (0.61) | PLAUF2PLGKLKB1PRSS1 | |
| Hydrochloric Acid SCHEMBL27473265 | 0.76 | ALDH1A1 (0.54) | APPABCB1ABCG2CYP2A6LOXL2 | |
| SCHEMBL16366949 | 0.76 | PLAU (0.48) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL13074509 | 0.75 | CYP2A6 (0.50) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL361389 | 0.75 | MAPT (0.53) | MEN1NPC1RAB9AKMT2AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114544571-B | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2023-04-18 | — | — | CN | claimed |
| CN-114544571-B | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-114544571-A | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2022-05-27 | — | — | CN | disclosed |