Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27473265 | 0.97 | ALDH1A1 (0.54) | LOXL2ALDH1A1CYP2A6APPMAPT | |
| Acetonitrile SCHEMBL9174267 | 0.95 | LOXL2 (0.50) | LOXL2ALDH1A1CYP2A6APPMAPT | |
| SCHEMBL13006754 | 0.93 | MMP3 (0.52) | LOXL2ALDH1A1CYP2A6APPMAPT | |
| SCHEMBL23742234 | 0.89 | SAE1 (0.62) | LOXL2ALDH1A1CYP2A6APPMAPT | |
| SCHEMBL21305525 | 0.87 | KDM4E (0.61) | LOXL2ALDH1A1CYP2A6APPMAPT | |
| SCHEMBL12994058 | 0.87 | APP (0.57) | LOXL2ALDH1A1APPLMNAKDM4E | |
| SCHEMBL14211448 | 0.87 | CYP1B1 (0.61) | LOXL2ALDH1A1CYP2A6APPMAPT | |
| SCHEMBL22198170 | 0.82 | ALDH1A1 (0.61) | LOXL2ALDH1A1APPMAPTLMNA | |
| SCHEMBL22270629 | 0.81 | APP (0.47) | LOXL2APPABCB1ABCG2MEN1 | |
| SCHEMBL14470303 | 0.81 | GSK3B (0.56) | ALDH1A1APPCA2CA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119194469-B | Method for electrochemically synthesizing amine compound | 山东金科力电源科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119194469-A | Method for electrochemically synthesizing amine compound | 山东金科力电源科技有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-115785044-B | Iminogenipin with uric acid reducing activity and preparation method and application thereof | 山东省华泰营养健康产业技术研究院有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-115785044-A | Iminogenipin with uric acid reducing activity and preparation method and application thereof | 山东省华泰营养健康产业技术研究院有限公司 | 2023-03-14 | — | — | CN | claimed |
| EP-3448850-B1 | PIPERIDINYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-10428024-B2 | Piperidinyl derivatives | MERCK PATENT GMBH (DE) | 2019-10-01 | — | — | US | claimed |
| US-20190135753-A1 | PIPERIDINYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-05-09 | — | — | US | claimed |
| EP-2593425-B1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | AGIOS PHARMACEUTICALS INC (US) | 2018-10-17 | — | — | EP | claimed |
| EP-3030554-B1 | PIPERIDINE UREA DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| US-20060293511-A1 | phosphinocarboxylate and phosphonocarboxylate oligonucleotides having enhanced nuclease resistance | LIEVRE CORNU LLC (US) | 2006-12-28 | — | — | US | claimed |
| US-7067641-B2 | Phosphinoamidite carboxylates and analogs thereof in the synthesis of oligonucleotides having reduced internucleotide charge | LIEVRE CORNU LLC (US) | 2006-06-27 | — | — | US | claimed |
| US-20040116687-A1 | oligonucleotides having reduced internucleotide charge and enhanced nuclease resistance | AGILENT TECHNOLOGIES, INC. | 2004-06-17 | — | — | US | claimed |
| US-5684148-A | NUCLEOSIDES AND POLYNUCLEOTIDES AS FLUORESCENT AGENTS FOR MEDICAL DIAGNOSIS | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-11-04 | — | — | US | claimed |
| US-5218103-A | Nucleoside thiophosphoramidites | UNIVERSITY PATENTS, INC. (US) | 1993-06-08 | — | — | US | claimed |
| EP-0378615-A4 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | — | 1992-04-08 | — | — | EP | claimed |
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | claimed |
| EP-0378615-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | COMPETITIVE TECHNOLOGIES INC. (US) | 1990-07-25 | — | — | EP | claimed |
| WO-1989011486-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1989-11-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428024-B2 | Piperidinyl derivatives | PDK1, PDK2, PDK3 | LOXL2 2659/4885ALDH1A1 82/4885CYP2A6 1764/4885 |
| US-20190135753-A1 | PIPERIDINYL DERIVATIVES | PDK1, PDK2, PDK3 | LOXL2 2659/4885ALDH1A1 82/4885CYP2A6 1764/4885 |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | LOXL2 3298/4885ALDH1A1 1278/4885CYP2A6 153/4885 |
| US-20060293511-A1 | phosphinocarboxylate and phosphonocarboxylate oligonucleotides having enhanced nuclease resistance | NSUN2, ADAR, POLL | LOXL2 612/4885ALDH1A1 3420/4885CYP2A6 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.