SCHEMBL296660

SCHEMBL296660

Oc1c(Br)c(Br)c(C2(c3c(Br)c(Br)c(O)c(Br)c3Br)CCCCC2)c(Br)c1Br

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ACHE P22303 1/20 0.38
ESR1 P03372 3/20 0.37
ESR2 Q92731 3/20 0.37
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
PTPN1 P18031 1/20 0.32
DRD4 P21917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL581828 0.80 ACHE (0.42) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL298773 0.67 MEN1 (0.41) ALDH1A1HPGDHSD17B10ACHEESR1
SCHEMBL297789 0.67 ACHE (0.47) ACHEESR1ESR2
SCHEMBL8371595 0.64 ACHE (0.59) ALDH1A1HPGDALOX15RECQLHIF1A
SCHEMBL297035 0.64 ACHE (0.59) ALDH1A1HPGDALOX15RECQLHIF1A
SCHEMBL297481 0.62 ACHE (0.42) ACHEESR1ESR2
Pentabromophenol SCHEMBL268325 0.62 ALOX15 (1.00) ALDH1A1HPGDALOX15MAPK1RECQL
Pentabromophenol SCHEMBL11697558 0.59 ALOX15 (0.91) ALDH1A1HPGDALOX15MAPK1RECQL
SCHEMBL6439410 0.59 CA1 (0.75) ALDH1A1HPGDALOX15MAPK1RECQL
SCHEMBL127379 0.59 ALOX15 (0.91) ALDH1A1HPGDALOX15MAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
CN-113166500-B Additive-containing polyethylene for increasing environmental stress cracking resistance SABIC环球技术有限责任公司 2024-11-08 CN disclosed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
US-20210388189-A1 POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-16 US disclosed
US-20210309839-A1 POLYETHYLENE WITH POLYCARBONATE-SILOXANE FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-07 US disclosed
WO-2003010219-A1 METHOD OF POLYCARBONATE PREPARATION BY SOLID STATE POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
US-6506871-B1 Ester interchange of bis(methyl salicyl) carbonate and bisphenol A in presence of tetrabutylphosphonium acetate catalyst GENERAL ELECTRIC COMPANY 2003-01-14 US disclosed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US disclosed
US-6420512-B1 SCREW EXTRUSION AND ESTER INTERCHANGE GENERAL ELECTRIC COMPANY 2002-07-16 US disclosed
US-20020035234-A1 Continuous preparation of polycarbonate GENERAL ELECTRIC COMPANY 2002-03-21 US disclosed
WO-2002008311-A2 CONTINUOUS PREPARATION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-01-31 WO disclosed