SCHEMBL297789

SCHEMBL297789

Cc1c(C)c(C2(c3c(C)c(C)c(O)c(C)c3C)CCCCC2)c(C)c(C)c1O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.47
ESR1 P03372 4/20 0.41
ESR2 Q92731 4/20 0.41
GLA P06280 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL581828 0.80 ACHE (0.42) ACHEESR1ESR2ALOX12
SCHEMBL297481 0.80 ACHE (0.42) ACHEESR1ESR2
SCHEMBL1176590 0.69 ACHE (0.58) ACHEESR1ESR2GLATSHR
SCHEMBL296660 0.67 ALDH1A1 (0.41) ACHEESR1ESR2
SCHEMBL298773 0.67 MEN1 (0.41) ACHEESR1ESR2TSHRLMNA
Durohydroquinone SCHEMBL69786 0.66 ALOX5 (0.38) ACHEALOX12
SCHEMBL23581823 0.64 ACHE (0.48) ACHEESR1ESR2
SCHEMBL11401705 0.64 ESR1 (0.44) ACHEESR1ESR2
SCHEMBL29993063 0.64 ESR1 (0.44) ACHEESR1ESR2
SCHEMBL11139078 0.64 ACHE (0.48) ACHEESR1ESR2GLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
CN-113166500-B Additive-containing polyethylene for increasing environmental stress cracking resistance SABIC环球技术有限责任公司 2024-11-08 CN disclosed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
US-20210388189-A1 POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-16 US disclosed
US-20210309839-A1 POLYETHYLENE WITH POLYCARBONATE-SILOXANE FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-07 US disclosed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US disclosed
US-6420512-B1 SCREW EXTRUSION AND ESTER INTERCHANGE GENERAL ELECTRIC COMPANY 2002-07-16 US disclosed
US-20020035234-A1 Continuous preparation of polycarbonate GENERAL ELECTRIC COMPANY 2002-03-21 US disclosed
WO-2002008311-A2 CONTINUOUS PREPARATION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-01-31 WO disclosed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO disclosed