Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666708 | 0.95 | OPRK1 (0.47) | ACEACE2OPRM1OPRD1OPRK1 | |
| SCHEMBL29701316 | 0.94 | ACE (0.49) | ACEACE2OPRM1OPRD1OPRK1 | |
| SCHEMBL30338091 | 0.92 | ACE (0.50) | ACEACE2 | |
| SCHEMBL29666705 | 0.90 | ACE (0.57) | ACEACE2OPRM1OPRD1OPRK1 | |
| SCHEMBL29630670 | 0.87 | TRHR (0.42) | ACEACE2OPRK1 | |
| SCHEMBL29666757 | 0.87 | ACE (0.50) | ACEACE2 | |
| SCHEMBL30383148 | 0.87 | OPRM1 (0.53) | OPRM1OPRD1 | |
| SCHEMBL31384593 | 0.87 | OPRK1 (0.56) | ACEACE2OPRK1 | |
| SCHEMBL29958712 | 0.87 | TRHR (0.41) | ACEACE2 | |
| SCHEMBL31347814 | 0.86 | C5AR1 (0.48) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | ANPEP, NPR3, XPNPEP1 | ACE 900/4885ACE2 1876/4885OPRM1 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.