Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 7/20 | 0.56 |
| ▸ | NPY4R | P50391 | 7/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.56 |
| ▸ | NPY1R | P25929 | 5/20 | 0.56 |
| ▸ | CALCR | P30988 | 8/20 | 0.55 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.55 |
| ▸ | APLNR | P35414 | 2/20 | 0.53 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409140 | 0.92 | APLNR (0.55) | NPY2RNPY4RNPY5RNPY1RCALCR | |
| SCHEMBL29836372 | 0.89 | C5AR1 (0.63) | NPY2RNPY4RNPY5RNPY1RCALCR | |
| SCHEMBL16212659 | 0.89 | C5AR1 (0.54) | APLNRC5AR1 | |
| SCHEMBL30504860 | 0.88 | C5AR1 (0.52) | APLNRC5AR1MAPK8MAPK9MAPK10 | |
| SCHEMBL30437136 | 0.87 | NPY2R (0.61) | NPY2RNPY4RNPY5RNPY1RCALCR | |
| SCHEMBL29678024 | 0.87 | OPRM1 (0.58) | CALCRAPLNRC5AR1 | |
| SCHEMBL38652641 | 0.87 | F2 (0.59) | NPY2RNPY4RNPY5RNPY1RCALCR | |
| Lusupultide SCHEMBL29359370 | 0.87 | CALCR (0.59) | CALCRAPLNRC5AR1MAPK8MAPK9 | |
| SCHEMBL31005065 | 0.87 | APLNR (0.55) | NPY2RNPY4RNPY5RNPY1RCALCR | |
| SCHEMBL31409175 | 0.86 | C5AR1 (0.53) | APLNRC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480233-B | Bioactive peptide IAHPKLGKRIR, and preparation method and application thereof | 上海交通大学 | 2022-05-27 | — | — | CN | claimed |
| CN-112480233-B | Bioactive peptide IAHPKLGKRIR, and preparation method and application thereof | 上海交通大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-112480233-B | Bioactive peptide IAHPKLGKRIR, and preparation method and application thereof | 上海交通大学 | 2022-05-27 | — | — | CN | disclosed |