Lusupultide

Lusupultide

SCHEMBL29359370

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)[C@@H](C)CC)C(C)C)C(C)C)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 4/20 0.59
▸ APLNR P35414 2/20 0.59
▸ C5AR1 P21730 1/20 0.56
▸ F2 P00734 4/20 0.56
▸ OPRM1 P35372 6/20 0.54
▸ OPRK1 P41145 6/20 0.54
▸ MAPK8 P45983 1/20 0.54
▸ MAPK9 P45984 1/20 0.54
▸ MAPK10 P53779 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296089 0.94 APLNR (0.61) CALCRAPLNRC5AR1F2MAPK8
SCHEMBL29679646 0.90 F2 (0.61) CALCRAPLNRF2
SCHEMBL29432915 0.90 MAPK8 (0.54) OPRM1OPRK1MAPK8MAPK9MAPK10
SCHEMBL31303836 0.89 CALCR (0.64) CALCRAPLNRC5AR1F2
SCHEMBL30495675 0.88 CALCR (0.60) CALCRAPLNRF2
SCHEMBL29597451 0.88 CALCR (0.66) CALCRF2
SCHEMBL30358178 0.88 CALCR (0.66) CALCR
SCHEMBL29678024 0.87 OPRM1 (0.58) CALCRAPLNRC5AR1OPRM1OPRK1
SCHEMBL29822539 0.87 F2 (0.62) CALCRAPLNRF2MAPK8MAPK9
SCHEMBL29667180 0.87 NPY2R (0.56) CALCRAPLNRC5AR1MAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 — — EP claimed
US-20240358939-A1 INTERNAL CANNULA MOUNTED NEBULIZER VAPOTHERM, INC. 2024-10-31 — — US claimed
EP-4034211-A1 INTERNAL CANNULA MOUNTED NEBULIZER Vapotherm, Inc. (US) 2022-08-03 — — EP claimed
CN-114728147-A Cannula internally mounted atomizer 蒸汽热能公司 2022-07-08 — — CN claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12624343-B2 Extracellular vesicles (EVs) derived from mesenchymal stromal cells and method for obtaining said EVs EXO BIOLOGICS SA (BE) 2026-05-12 — — US disclosed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 — — EP disclosed
US-12616695-B2 Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of rare chronic inflammatory pulmonary diseases METRIOPHARM AG (CH) 2026-05-05 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
EP-3481958-B1 METHODS AND COMPOSITIONS FOR TREATMENT OF DISORDERS AND DISEASES INVOLVING RDH12 UNIV PENNSYLVANIA (US) 2026-04-01 — — EP disclosed
EP-3668319-B1 PURIFIED MESENCHYMAL STEM CELL EXOSOMES AND USES THEREOF CHILDRENS MEDICAL CENTER (US) 2026-03-25 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
US-20220049275-A1 SSI CELLS WITH PREDICTABLE AND STABLE TRANSGENE EXPRESSION AND METHODS OF FORMATION LONZA AG (CH) 2022-02-17 — — US disclosed
US-20220042064-A1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA LTD (CH) 2022-02-10 — — US disclosed
EP-3947695-A1 MUT- METHYLOTROPHIC YEAST Universität für Bodenkultur Wien (AT) 2022-02-09 — — EP disclosed
US-11236520-B2 Customizable facility LONZA LTD (CH) 2022-02-01 — — US disclosed
US-20220023347-A9 PURIFIED MESENCHYMAL STEM CELL EXOSOMES AND USES THEREOF CHILDREN'S MEDICAL CENTER CORPORATION (US) 2022-01-27 — — US disclosed
EP-3942014-A1 CONTINUOUS BLADE IMPELLER Lonza Ltd. (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS CALCR 2542/4885APLNR 354/4885C5AR1 1317/4885
US-12624343-B2 Extracellular vesicles (EVs) derived from mesenchymal stromal cells and method for obtaining said EVs CD63, TFRC, EXOSC9 CALCR 3300/4885APLNR 2047/4885C5AR1 1733/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 CALCR 1795/4885APLNR 947/4885C5AR1 2673/4885
US-12616695-B2 Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of rare chronic inflammatory pulmonary diseases CRYZ, PDE12, FKBP5 CALCR 4542/4885APLNR 4063/4885C5AR1 3784/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT CALCR 1581/4885APLNR 1687/4885C5AR1 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback