Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14117385 | 0.94 | ADRB2 (0.49) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL13240114 | 0.85 | ADRB2 (0.42) | ADRB2ADRB1ROCK2ROCK1 | |
| SCHEMBL1230900 | 0.85 | ADRB2 (0.63) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL14190089 | 0.83 | ADRB2 (0.42) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL7775809 | 0.83 | ADRB2 (0.56) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL7778381 | 0.83 | ADRB2 (0.56) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL5145221 | 0.83 | ADRB2 (0.56) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL14141543 | 0.80 | ADRB2 (0.62) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL6258012 | 0.79 | ADRB2 (0.50) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL6838978 | 0.78 | ADRB2 (0.66) | ADRB2HIF1ATSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759392-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20090170941-A1 | Pharmaceutical Compounds | NICOX S.A. (FR) | 2009-07-02 | — | — | US | disclosed |
| US-7399878-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-07-15 | — | — | US | disclosed |
| US-20070197499-A1 | Pharmaceutical compounds | NICOX S.A. | 2007-08-23 | — | — | US | disclosed |
| US-7186753-B1 | Pharmaceutical compounds | NICOX S.A. (FR) | 2007-03-06 | — | — | US | disclosed |
| EP-1593664-A1 | Nitric esters derivatives of ferulic acid and sulindac with pharmaceutical activity | Nicox S.A (FR) | 2005-11-09 | — | — | EP | disclosed |
| EP-1252133-B1 | PHARMACEUTICAL COMPOUNDS | NICOX SA (FR) | 2005-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197499-A1 | Pharmaceutical compounds | NR0B2, NR0B1, CYP11B2 | ADRB2 16/4885HIF1A 2937/4885TSHR 371/4885 |
| US-20090170941-A1 | Pharmaceutical Compounds | NR0B2, NR0B1, CYP11B2 | ADRB2 16/4885HIF1A 2760/4885TSHR 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.