Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYCS | P99999 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38286 | 1.00 | TOP1 (0.46) | TOP1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL29660282 | 1.00 | TOP1 (0.46) | TOP1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL10337099 | 0.98 | TOP1 (0.45) | TOP1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL8349653 | 0.92 | TOP1 (0.51) | TOP1ALDH1A1HSD17B10TERTCYCS | |
| SCHEMBL28121945 | 0.92 | TOP1 (0.51) | TOP1ALDH1A1HSD17B10TERTCYCS | |
| SCHEMBL27958995 | 0.92 | TOP1 (0.51) | TOP1ALDH1A1HSD17B10TERTCYCS | |
| SCHEMBL29714914 | 0.92 | TOP1 (0.51) | TOP1ALDH1A1HSD17B10TERTCYCS | |
| SCHEMBL9388930 | 0.87 | TOP1 (0.50) | TOP1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7261395 | 0.84 | TOP1 (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL5011854 | 0.82 | STAT3 (0.60) | TOP1ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260085299-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-01-29 | — | — | US | disclosed |
| CN-112469357-B | Method and system for in situ exchange | 杰尼索尼克斯公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-119816897-A | Multiple study assessment | 普罗科技有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119110706-A | Disease detection device | 艾恩娜诊断有限公司 | 2024-12-10 | — | — | CN | disclosed |
| US-20240368202-A1 | REDUCING AGENTS AND USES THEREOF | Singular Genomics Systems, Inc. | 2024-11-07 | — | — | US | disclosed |
| CN-113762997-B | Information generation method, device, system and storage medium | 北京沃东天骏信息技术有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-117591306-A | Custom system message pushing method, device, equipment and storage medium | 上海韵达高新技术有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117396983-A | Multiple study assessment | 普罗科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-110019754-B | Knowledge base building method, device and equipment | 创新先进技术有限公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-4248605-A1 | OPTIMIZING USER EXPERIENCE IN ENCRYPTED TRAFFIC | Telefonaktiebolaget LM Ericsson (publ) (SE) | 2023-09-27 | — | — | EP | disclosed |
| CN-113448746-B | Configuration processing method, configuration platform and related equipment | 北京新氧科技有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116669635-A | Systems and methods for image-guided tissue ablation | 杰尼索尼克斯公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115661301-A | Method for adding annotations, electronic device, storage medium and program product | 华为技术有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115065687-A | Cross-chain data sharing method and system between HyperLegend Fabric and Ether FaorIn | 中国科学院计算技术研究所 | 2022-09-16 | — | — | CN | disclosed |
| CN-114805527-A | RAS inhibitory peptides and uses thereof | 哈佛大学的校长及成员们 | 2022-07-29 | — | — | CN | disclosed |
| WO-2022108496-A1 | OPTIMIZING USER EXPERIENCE IN ENCRYPTED TRAFFIC | TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368202-A1 | REDUCING AGENTS AND USES THEREOF | GPX4, LPO, NOX4 | TOP1 3101/4885ALDH1A1 173/4885NPC1 1262/4885 |
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | POLL, POLB, POLN | TOP1 71/4885ALDH1A1 2325/4885NPC1 3739/4885 |
| US-20260085299-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | POLB, POLM, POLRMT | TOP1 204/4885ALDH1A1 4563/4885NPC1 4713/4885 |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | POLN, NSUN2, POLL | TOP1 16/4885ALDH1A1 2370/4885NPC1 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.