Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28708840 | 1.00 | KMT2A (0.55) | KMT2AALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL29670966 | 0.88 | MAPT (0.57) | KMT2AALDH1A1KDM4EMEN1RAB9A | |
| SCHEMBL28715922 | 0.88 | MAPT (0.57) | KMT2AALDH1A1KDM4EMEN1RAB9A | |
| SCHEMBL29670970 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1MEN1RAB9ANPC1 | |
| SCHEMBL28718270 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1MEN1RAB9ANPC1 | |
| SCHEMBL29670956 | 0.83 | TP53 (0.50) | KMT2AALDH1A1KDM4EMEN1RAB9A | |
| SCHEMBL28708838 | 0.83 | TP53 (0.50) | KMT2AALDH1A1KDM4EMEN1RAB9A | |
| SCHEMBL28705641 | 0.83 | MAPT (0.52) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL29670957 | 0.83 | MAPT (0.52) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL29670982 | 0.82 | ALDH1A1 (0.57) | KMT2AALDH1A1RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |