Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707733 | 1.00 | MAPT (0.51) | MAPTKMT2AMEN1SMN1; SMN2GFER | |
| SCHEMBL28719380 | 0.80 | MAPT (0.55) | MAPTKMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL29670976 | 0.80 | MAPT (0.55) | MAPTKMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28937215 | 0.80 | MMP2 (0.52) | MAPTSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL29670974 | 0.80 | MMP2 (0.52) | MAPTSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL28719007 | 0.79 | MMP2 (0.46) | MAPTSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL29670975 | 0.79 | MMP2 (0.46) | MAPTSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL4863134 | 0.79 | MEN1 (0.69) | MAPTKMT2AMEN1SMN1; SMN2GFER | |
| SCHEMBL28705641 | 0.78 | MAPT (0.52) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29670957 | 0.78 | MAPT (0.52) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |