Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 8/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671340 | 0.86 | APLNR (0.61) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL29671219 | 0.85 | APLNR (0.51) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL29671186 | 0.84 | APLNR (0.50) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL29665769 | 0.83 | APLNR (0.49) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL29671208 | 0.81 | APLNR (0.47) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL29671255 | 0.80 | TAS2R14 (0.53) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL29665682 | 0.80 | APLNR (0.54) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL31034551 | 0.77 | APLNR (0.56) | APLNRTAS2R14CNR2HDAC6HDAC11 | |
| SCHEMBL27020194 | 0.77 | TAS2R14 (0.59) | APLNRTAS2R14HDAC6HDAC11HDAC8 | |
| SCHEMBL31034596 | 0.76 | APLNR (0.52) | APLNRTAS2R14CNR2HDAC6HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017843-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 Ontario, Inc. (CA) | 2022-06-29 | — | — | EP | disclosed |
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |