SCHEMBL2967151

SCHEMBL2967151

CCCCCCc1c(CC)c(CC)c2cc(C(=O)O)ccc2c1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.47
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
RARA P10276 1/20 0.46
MAPT P10636 1/20 0.46
MTOR P42345 1/20 0.46
KMT2A Q03164 1/20 0.46
LDHA P00338 1/20 0.44
LDHB P07195 1/20 0.44
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
PLA2G4B P0C869 1/20 0.43
BID P55957 1/20 0.41
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41
BAK1 Q16611 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670029 0.90 RARB (0.50) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL290671 0.90 RARB (0.50) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL168254 0.83 BID (0.48) ALDH1A1MAPTBIDBCL2L1MCL1
SCHEMBL29138979 0.78 BID (0.54) ALDH1A1MAPTBIDBCL2L1MCL1
SCHEMBL11094349 0.76 ALDH1A1 (0.53) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL18543774 0.75 RARB (0.49) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL28496833 0.75 RARB (0.49) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL1615392 0.73 BID (0.49) ALDH1A1MAPTBIDBCL2L1MCL1
SCHEMBL7944628 0.73 BID (0.46) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL18481326 0.73 OXER1 (0.44) ALDH1A1LDHALDHBBIDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2193785-B1 Extracts of Tetraselmis sp. for cosmetic and therapeutic purposes SYMRISE AG (DE) 2018-07-18 EP disclosed
US-9445988-B2 Extracts of Tetraselmis sp SYMRISE AG (DE) 2016-09-20 US disclosed
EP-2168570-B1 Extracts of isochrysis sp. SYMRISE AG (DE) 2013-12-25 EP disclosed
EP-1954831-B1 AHR MEDIATOR SYMRISE AG (DE) 2012-07-11 EP disclosed
US-20100143267-A1 EXTRACTS OF TETRASELMIS SP. SYMRISE GMBH & CO. KG (DE) 2010-06-10 US disclosed
EP-2193785-A2 Extracts of Tetraselmis sp. for cosmetic and therapeutic purposes Symrise GmbH & Co. KG (DE) 2010-06-09 EP disclosed
EP-2168570-A2 Extracts of isochrysis sp. Symrise GmbH & Co. KG (DE) 2010-03-31 EP disclosed
US-20080305054-A1 Use of Glycosylated Flavanones for the Browning of Skin or Hair SYMRISE GMBH & CO. KG (DE) 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305054-A1 Use of Glycosylated Flavanones for the Browning of Skin or Hair FUT6, FUT5, DPM1 RARB 1481/4885MEN1 2135/4885ALDH1A1 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.