SCHEMBL290671

SCHEMBL290671

CCCCCCc1c(C(=O)O)c(CC)c(CC)c2cc(C(=O)O)ccc12

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.50
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
RARA P10276 1/20 0.46
MAPT P10636 1/20 0.46
MTOR P42345 1/20 0.46
KMT2A Q03164 1/20 0.46
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
PLA2G4B P0C869 1/20 0.43
LDHA P00338 1/20 0.41
LDHB P07195 1/20 0.41
BID P55957 1/20 0.41
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41
BAK1 Q16611 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670029 1.00 RARB (0.50) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL2967151 0.90 RARB (0.47) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL1615392 0.85 BID (0.49) ALDH1A1MAPTBIDBCL2L1MCL1
SCHEMBL18543774 0.78 RARB (0.49) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL28496833 0.78 RARB (0.49) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL11094349 0.76 ALDH1A1 (0.53) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL168254 0.75 BID (0.48) ALDH1A1MAPTBIDBCL2L1MCL1
SCHEMBL7944628 0.73 BID (0.46) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL18481326 0.73 OXER1 (0.44) ALDH1A1LDHALDHBBIDBCL2L1
SCHEMBL6383337 0.73 KAT8 (0.46) RARBMAPTBIDBCL2L1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173229-A1 METHODS OF SKIN WHITENING BY USE OF CANOLA EXTRACTS 1242753 ONTARIO INC (CA) 2024-05-30 US claimed
EP-3348251-B1 SUNSCREEN COMPOSITIONS GLAXOSMITHKLINE CONSUMER HEALTHCARE HOLDINGS US LLC (US) 2024-01-17 EP claimed
EP-4223279-A1 METHODS OF SKIN WHITENENING BY USE OF CANOLA EXTRACTS 1242753 Ontario Inc. (CA) 2023-08-09 EP claimed
WO-2022192882-A9 TOPICAL COMPOSITIONS FOR UV PROTECTION MARY KAY INC. (US) 2023-03-23 WO claimed
EP-3578558-B1 HIGHLY EFFECTIVE PHOTOPROTECTIVE AGENTS 3V SIGMA SPA (IT) 2021-02-24 EP claimed
EP-2961370-B1 MICROCAPSULES COMPRISING SUNSCREEN AGENTS TAGRA BIOTECHNOLOGIES LTD (IL) 2020-12-23 EP claimed
EP-3578558-A1 HIGHLY EFFECTIVE PHOTOPROTECTIVE AGENTS 3V SIGMA S.p.A (IT) 2019-12-11 EP claimed
EP-2853255-B1 Method of formulating a personal care product with substantially no whitening effect when applied on wet skin and compositions thereof HallStar Beauty and Personal Care Innovations Company (US) 2018-11-28 EP claimed
EP-2488151-B1 SUNSCREEN COMPOSITIONS WYETH LLC (US) 2018-02-28 EP claimed
EP-2427182-B1 TOPICAL COMPOSITIONS COMPRISING INORGANIC PARTICULATES AND AN ALKOXYLATED DIPHENYLACRYLATE COMPOUND ELC MAN LLC (US) 2017-01-11 EP claimed
WO-2005065136-A2 OIL IN SILICONE EMULSIONS AND COMPOSITIONS CONTAINING SAME AVON PRODUCTS, INC. (US) 2005-07-21 WO claimed
US-20050142079-A1 Oil in silicone emulsion and compositions containing same AVON PRODUCTS INC. 2005-06-30 US claimed
US-20050136014-A1 Novel esters of aryl benzimidazole sulfonic acids and sunscreen compositions containing same AVON PRODUCTS INC. 2005-06-23 US claimed
EP-1458339-A1 COSMETIC AND DERMATOLOGICAL LIGHT PROTECTION FORMULATIONS HAVING A CONTENT OF BENZOXAZOL DERIVATIVES Beiersdorf AG (DE) 2004-09-22 EP claimed
WO-2003084496-A1 LIGHT-PROTECTIVE PREPARATIONS CONTAINING A PHOTOSTABLE UV-A FILTER SYMRISE GMBH & CO. KG (DE) 2003-10-16 WO claimed
WO-2003053390-A1 COSMETIC AND DERMATOLOGICAL LIGHT PROTECTION FORMULATIONS HAVING A CONTENT OF BENZOXAZOL DERIVATIVES BEIERSDORF AG (DE) 2003-07-03 WO claimed
EP-1323410-A2 Sunscreen emulsion composition and method of use AVON PRODUCTS, INC. (US) 2003-07-02 EP claimed
WO-2003051279-A2 TOPICAL COMPOSITIONS AND METHODS OF APPLICATION AVON PRODUCTS, INC. (US) 2003-06-26 WO claimed
US-6555095-B1 Containing a compound: L-A-H and A-L-H, wherein L is a lipophilic moiety, wherein A is an aromatic moiety having an ultraviolet absorption maximum between 290 nanometers and 400 nanometers, and wherein H is a hydrophilic moiety AVON PRODUCTS, INC. 2003-04-29 US claimed
US-6517816-B1 Inner discontinuous phase and an outer continuous phase AVON PRODUCTS, INC. 2003-02-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136014-A1 Novel esters of aryl benzimidazole sulfonic acids and sunscreen compositions containing same TYR, NISCH, CUTA RARB 108/4885MEN1 3495/4885ALDH1A1 599/4885
US-20050142079-A1 Oil in silicone emulsion and compositions containing same CUTA, SRR, SMURF1 RARB 336/4885MEN1 1976/4885ALDH1A1 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.