Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CHKA | P35790 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591420 | 1.00 | ALDH1A1 (0.64) | ALDH1A1TDP1KDM4EPOLBNR1H2 | |
| SCHEMBL4297559 | 0.87 | LMNA (0.60) | ALDH1A1TDP1KDM4EPOLBNR1H2 | |
| SCHEMBL4935736 | 0.87 | MAPT (0.57) | ALDH1A1TDP1KDM4EPOLBNR1H2 | |
| SCHEMBL2208032 | 0.85 | ACHE (0.60) | ALDH1A1TDP1KDM4EPOLBNR1H2 | |
| SCHEMBL2656580 | 0.83 | KDM4E (0.88) | ALDH1A1TDP1KDM4EPOLBCHKA | |
| SCHEMBL3859176 | 0.83 | ACHE (0.58) | ALDH1A1TDP1KDM4EPOLBCHKA | |
| SCHEMBL17918745 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TDP1KDM4EPOLBNR1H2 | |
| SCHEMBL4758225 | 0.82 | NR1H2 (0.64) | ALDH1A1TDP1KDM4EPOLBNR1H2 | |
| SCHEMBL3862744 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TDP1KDM4EPOLBMAPT | |
| SCHEMBL3916828 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1KDM4EPOLBNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573567-B | Indazole cyclotriazole compound and preparation method and application thereof | 西安交通大学 | 2023-05-02 | — | — | CN | claimed |
| CN-114573567-A | Indazole cyclic triazole compound and preparation method and application thereof | 西安交通大学 | 2022-06-03 | — | — | CN | claimed |
| US-20250361232-A1 | SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS | TAKEDA PHARMACEUTICALS USA INC (US) | 2025-11-27 | — | — | US | disclosed |
| CN-114573567-B | Indazole cyclotriazole compound and preparation method and application thereof | 西安交通大学 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022226182-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-27 | — | — | WO | disclosed |
| CN-114573567-A | Indazole cyclic triazole compound and preparation method and application thereof | 西安交通大学 | 2022-06-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361232-A1 | SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS | MAP4K2, MAP3K19, MAP3K1 | ALDH1A1 980/4885TDP1 1725/4885KDM4E 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.