SCHEMBL2967202

SCHEMBL2967202

O=C1CCc2cc(C(=O)c3c(O)cc(O)cc3F)ccc2O1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.36
FASN P49327 1/20 0.34
SYNJ2 O15056 1/20 0.34
HSD17B1 P14061 2/20 0.33
CLK1 P49759 1/20 0.33
DYRK1A Q13627 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
CTNNB1 P35222 1/20 0.32
WNT3A P56704 1/20 0.32
ALDH1A1 P00352 3/20 0.32
RAB9A P51151 2/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2968672 0.82 PTGS2 (0.36) MAOBHSD17B1CLK1DYRK1ADYRK1B
SCHEMBL2957000 0.80 MEN1 (0.47) MAOBALDH1A1USP2LMNAGAA
SCHEMBL2965162 0.73 PTGS2 (0.42) MAOBHSD17B1CLK1DYRK1ADYRK1B
SCHEMBL14430960 0.73 ALDH1A1 (0.49) MAOBCTNNB1WNT3AALDH1A1MEN1
SCHEMBL12104205 0.72 TSHR (0.49) MAOBALDH1A1RAB9AHSD17B10NPC1
SCHEMBL19198564 0.72 NPC1 (0.47) MAOBHSD17B1RAB9AHPGDNPC1
SCHEMBL3754190 0.71 PTGS2 (0.51) MAOBALDH1A1RAB9AGAAHPGD
SCHEMBL30749724 0.71 PTGS2 (0.51) MAOBALDH1A1RAB9AGAAHPGD
SCHEMBL30726848 0.69 CA12 (0.56) MAOBALDH1A1RAB9AGAAHPGD
SCHEMBL18114087 0.69 ALDH1A1 (0.48) CTNNB1WNT3AALDH1A1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1445249-B1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-07 EP disclosed
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
EP-1445249-A1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2004-08-11 EP disclosed