Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749724 | 1.00 | PTGS2 (0.51) | PTGS2PBRM1ESR1ESR2ALDH1A1 | |
| SCHEMBL1013856 | 0.85 | CA2 (0.50) | PBRM1ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL29448284 | 0.85 | CA2 (0.50) | PBRM1ESR1ESR2ALDH1A1HPGD | |
| Homogenestic Acid Lactone SCHEMBL31756861 | 0.82 | MAOA (0.49) | PTGS2ALDH1A1HPGDHSD17B10GAA | |
| Homogenestic Acid Lactone SCHEMBL2460842 | 0.82 | MAOA (0.49) | PTGS2ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL1984098 | 0.81 | AHR (0.43) | HPGDHSD17B10MAOAMAOBGLA | |
| SCHEMBL2957000 | 0.80 | MEN1 (0.47) | PTGS2ALDH1A1HPGDGAAMAOA | |
| SCHEMBL2965162 | 0.79 | PTGS2 (0.42) | PTGS2ALDH1A1HPGDMAOAMAOB | |
| SCHEMBL9289705 | 0.78 | PTGS2 (0.46) | PTGS2PBRM1ESR1ESR2ALDH1A1 | |
| SCHEMBL19227826 | 0.78 | ALDH2 (0.39) | PTGS2HPGDHSD17B10MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587583-A1 | COVALENTLY MODIFIED TEMPLATE-INDEPENDENT DNA POLYMERASE AND METHODS OF USE THEREOF | The Charles Stark Draper Laboratory, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059703-A1 | COVALENTLY MODIFIED TEMPLATE-INDEPENDENT DNA POLYMERASE AND METHODS OF USE THEREOF | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-117511579-A | Biomass pyrolysis method and device | 华陆工程科技有限责任公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2021-02-04 | — | — | US | disclosed |
| US-9620363-B2 | Underlayer film-forming composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-04-11 | — | — | US | disclosed |
| US-9620363-B2 | Underlayer film-forming composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-04-11 | — | — | US | disclosed |
| US-20160339263-A1 | SKIN LIGHTENER IN PHOTOTHERAPY | MERCK PATENT GMBH (DE) | 2016-11-24 | — | — | US | disclosed |
| EP-2813891-A2 | Photoresist underlayer film-forming composition and pattern forming process | Shin-Etsu Chemical Co., Ltd. (JP) | 2014-12-17 | — | — | EP | disclosed |
| US-20140363956-A1 | UNDERLAYER FILM-FORMING COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140363956-A1 | UNDERLAYER FILM-FORMING COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-12-11 | — | — | US | disclosed |
| EP-0912534-A1 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000412-A9 | MUSCARINIC ANTAGONISTS | — | 1998-07-09 | — | — | WO | disclosed |
| WO-1998000412-A1 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 1998-01-08 | — | — | WO | disclosed |
| CN-1106013-A | Therapeutic or preventive agents for diseases associated with peroxyli peroxylipid | MITSUI TOATSU CHEMICALS (JP) | 1995-08-02 | — | — | CN | disclosed |
| US-5434186-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1995-07-18 | — | — | US | disclosed |
| US-5273999-A | A 4-keto-boroalkyleneoxychroman or 2,3-dihydrobenzofuran derivative | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0531823-A1 | Bicyclic carboxylic acid derivatives as anti-inflammatory agents | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| US-4780478-A | Aminopropoxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 1988-10-25 | — | — | US | disclosed |
| US-4508732-A | Basic ethers useful as antidepressant agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-02 | — | — | US | disclosed |
| US-4376123-A | Hexahydroazepinyloxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | KMO, FFAR3, ACOX3 | PTGS2 2044/4885PBRM1 3330/4885ESR1 2896/4885 |
| US-20160339263-A1 | SKIN LIGHTENER IN PHOTOTHERAPY | TYR, MC1R, CUTA | PTGS2 590/4885PBRM1 3050/4885ESR1 2509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.