SCHEMBL2965162

SCHEMBL2965162

Cc1cc(O)ccc1C(=O)c1ccc2c(c1)CCC(=O)O2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.42
ALDH2 P05091 1/20 0.39
ALDH3A1 P30838 1/20 0.39
KMT2A Q03164 5/20 0.38
MAPT P10636 5/20 0.38
MEN1 O00255 4/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
NPC1 O15118 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
HTT P42858 2/20 0.37
GLA P06280 1/20 0.36
THRB P10828 2/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CTNNB1 P35222 1/20 0.35
WNT3A P56704 1/20 0.35
HSD17B1 P14061 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2957000 0.88 MEN1 (0.47) PTGS2KMT2AMAPTMEN1ALDH1A1
SCHEMBL2968672 0.86 PTGS2 (0.36) PTGS2KMT2AMAPTMEN1ALDH1A1
SCHEMBL30749724 0.79 PTGS2 (0.51) PTGS2ALDH2ALDH3A1KMT2AMAPT
SCHEMBL3754190 0.79 PTGS2 (0.51) PTGS2ALDH2ALDH3A1KMT2AMAPT
SCHEMBL19198564 0.76 NPC1 (0.47) ALDH2ALDH3A1MAPTHPGDNPC1
SCHEMBL14430960 0.74 ALDH1A1 (0.49) ALDH2ALDH3A1KMT2AMAPTMEN1
SCHEMBL2961235 0.74 JUN (0.43) MAPTALDH1A1HPGDNPC1SMN1; SMN2
SCHEMBL2967202 0.73 MAOB (0.36) PTGS2ALDH2ALDH3A1KMT2AMEN1
SCHEMBL12104205 0.73 TSHR (0.49) ALDH2ALDH3A1ALDH1A1NPC1SMN1; SMN2
SCHEMBL30726848 0.72 CA12 (0.56) KMT2AMAPTMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101402562-B Novel benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO LTD 2013-07-31 CN disclosed
EP-1445249-B1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-07 EP disclosed
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
CN-101054345-B Novel bensophenone derivatives or salts thereof TOYAMA CHEMICAL CO LTD 2010-06-02 CN disclosed
CN-1602291-B Novel benzophenone derivative or salt thereof TOYAMA CHEMICAL CO LTD 2010-05-12 CN disclosed
CN-101402562-A Novel benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO LTD (JP) 2009-04-08 CN disclosed
CN-101054345-A Novel bensophenone derivatives or salts thereof TOYAMA CHEMICAL CO LTD (JP) 2007-10-17 CN disclosed
CN-1602291-A Novel benzophenone derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2005-03-30 CN disclosed
EP-1445249-A1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2004-08-11 EP disclosed