Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768664 | 1.00 | MAPT (0.50) | MAPTALDH1A1LMNAKCNH2CNR1 | |
| SCHEMBL20213112 | 0.86 | KCNH2 (0.48) | MAPTALDH1A1LMNAKCNH2CNR1 | |
| SCHEMBL29673141 | 0.85 | KCNH2 (0.48) | MAPTALDH1A1LMNAKCNH2CNR1 | |
| SCHEMBL28766422 | 0.85 | KCNH2 (0.48) | MAPTALDH1A1LMNAKCNH2CNR1 | |
| SCHEMBL29724324 | 0.83 | MAPT (0.45) | MAPTALDH1A1LMNAPOLBCYP1A2 | |
| SCHEMBL28766617 | 0.83 | GPR119 (0.41) | MAPTALDH1A1LMNAKCNH2MAPK1 | |
| SCHEMBL28766620 | 0.83 | GPR119 (0.41) | MAPTALDH1A1LMNAKCNH2MAPK1 | |
| SCHEMBL29673092 | 0.83 | GPR119 (0.41) | MAPTALDH1A1LMNAKCNH2MAPK1 | |
| SCHEMBL22720253 | 0.81 | KCNH2 (0.42) | MAPTALDH1A1LMNAKCNH2CNR1 | |
| SCHEMBL1693887 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAKCNH2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245046-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| WO-2022127827-A1 | KRASG12C PROTEIN MUTATION INHIBITOR AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 上海维申医药有限公司 | 2022-06-23 | — | — | WO | disclosed |
| CN-114644631-A | KRAS G12C protein mutation inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-06-21 | — | — | CN | disclosed |