Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29339261 | 0.87 | CYP1A2 (0.46) | ALDH1A1HPGDNPC1LMNAMAPT | |
| SCHEMBL5743082 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL29675690 | 0.83 | ALDH1A1 (0.51) | MTNR1AMTNR1BALDH1A1NPC1LMNA | |
| SCHEMBL14519898 | 0.83 | ALDH1A1 (0.51) | MTNR1AMTNR1BALDH1A1NPC1LMNA | |
| SCHEMBL16906730 | 0.80 | LMNA (0.49) | MTNR1AMTNR1BALDH1A1HPGDNPC1 | |
| SCHEMBL23343879 | 0.77 | P2RX7 (0.50) | ALDH1A1HPGDMAPTMAPK1RAB9A | |
| SCHEMBL20720156 | 0.77 | ALDH1A1 (0.42) | MTNR1AMTNR1BALDH1A1NPC1LMNA | |
| SCHEMBL20720155 | 0.77 | ALDH1A1 (0.42) | MTNR1AMTNR1BALDH1A1NPC1LMNA | |
| SCHEMBL30226117 | 0.77 | ALDH1A1 (0.42) | MTNR1AMTNR1BALDH1A1NPC1LMNA | |
| SCHEMBL14519899 | 0.76 | KIF11 (0.43) | MTNR1AMTNR1BALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |