Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675681 | 0.84 | ROCK2 (0.34) | L3MBTL1NPC1RAB9ANNMTMAPK1 | |
| SCHEMBL20001449 | 0.74 | NNMT (0.35) | NNMTABL1HCAR3 | |
| SCHEMBL29675753 | 0.72 | NPC1 (0.47) | L3MBTL1NPC1RAB9AACACBACACA | |
| SCHEMBL18497252 | 0.70 | MAPT (0.43) | L3MBTL1NPC1RAB9AACACBGPR139 | |
| SCHEMBL22995195 | 0.69 | CACNA1I (0.40) | — | |
| SCHEMBL31036987 | 0.69 | NPC1 (0.40) | L3MBTL1NPC1RAB9AMAPK1ACACB | |
| SCHEMBL19658639 | 0.69 | CNR2 (0.49) | L3MBTL1NPC1RAB9A | |
| SCHEMBL12656605 | 0.68 | NPC1 (0.40) | L3MBTL1NPC1RAB9AACACBACACA | |
| SCHEMBL19323041 | 0.68 | RAB9A (0.54) | L3MBTL1NPC1RAB9AMAPK1ALOX12 | |
| SCHEMBL1819387 | 0.68 | POLB (0.46) | L3MBTL1NPC1RAB9AACACBGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |