Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.34 |
| ▸ | NNMT | P40261 | 2/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675930 | 0.84 | L3MBTL1 (0.43) | NNMTNPC1RAB9AL3MBTL1MAPK1 | |
| SCHEMBL29676238 | 0.76 | MAPK1 (0.44) | NPC1RAB9AL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL29675755 | 0.74 | L3MBTL1 (0.38) | ROCK2ROCK1NPC1RAB9AL3MBTL1 | |
| SCHEMBL31036988 | 0.71 | CNR2 (0.47) | ROCK2ROCK1GPR88 | |
| SCHEMBL20001449 | 0.69 | NNMT (0.35) | NNMTABL1HCAR3 | |
| SCHEMBL29675928 | 0.68 | KCNH2 (0.40) | NPC1RAB9AL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31592659 | 0.65 | CTSA (0.40) | ROCK2ROCK1GPR88MAPK1 | |
| SCHEMBL29676240 | 0.65 | CYP3A4 (0.35) | NPC1RAB9AL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31037004 | 0.64 | SLC6A9 (0.47) | SMN1; SMN2KDM4E | |
| SCHEMBL19323950 | 0.64 | ALDH1A1 (0.49) | NPC1RAB9AL3MBTL1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |