Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963190 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL4612610 | 0.82 | NQO2 (0.47) | ALDH1A1NQO2HPGDNQO1MAPT | |
| SCHEMBL10866616 | 0.82 | RAB9A (0.38) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL17310947 | 0.81 | CYP1A2 (0.56) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL11810667 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL31362057 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL5686498 | 0.79 | TUBB1 (0.67) | NQO2KMT2A | |
| SCHEMBL5686446 | 0.79 | TUBB1 (0.67) | NQO2KMT2A | |
| SCHEMBL5686445 | 0.79 | TUBB1 (0.67) | NQO2KMT2A | |
| SCHEMBL29164128 | 0.79 | MAPT (0.57) | ALDH1A1TSHRTTRERN1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003959-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | Bayer AS (NO) | 2022-06-01 | — | — | EP | disclosed |