Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678864 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL4612610 | 0.82 | NQO2 (0.47) | ALDH1A1NQO2HPGDNQO1MAPT | |
| SCHEMBL10866616 | 0.82 | RAB9A (0.38) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL17310947 | 0.81 | CYP1A2 (0.56) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL11810667 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL31362057 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TSHRTTRERN1NQO2 | |
| SCHEMBL5686498 | 0.79 | TUBB1 (0.67) | NQO2KMT2A | |
| SCHEMBL5686446 | 0.79 | TUBB1 (0.67) | NQO2KMT2A | |
| SCHEMBL5686445 | 0.79 | TUBB1 (0.67) | NQO2KMT2A | |
| SCHEMBL29164128 | 0.79 | MAPT (0.57) | ALDH1A1TSHRTTRERN1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230072421-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | BAYER AS (NO) | 2023-03-09 | — | — | US | disclosed |
| EP-4003959-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | Bayer AS (NO) | 2022-06-01 | — | — | EP | disclosed |
| WO-2021013978-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | BAYER AS (NO) | 2021-01-28 | — | — | WO | disclosed |
| CN-106673988-B | Benzyl subunit cyclohexenone derivative and preparation method and medical application thereof | 南通大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-107162930-B | Fluorescence probe of superoxide anion and its preparation method and application, fibre-optical probe and preparation method thereof for identification | 黄淮学院 | 2019-11-22 | — | — | CN | disclosed |
| CN-107162930-A | Fluorescence probe for recognizing superoxide anion and its preparation method and application, fibre-optical probe and preparation method thereof | 黄淮学院 | 2017-09-15 | — | — | CN | disclosed |
| CN-106673988-A | Benzyl cyclohexenone derivative and preparation method and medical application thereof | 南通大学 | 2017-05-17 | — | — | CN | disclosed |
| US-7071225-B2 | Arylaminopropane analogues and their use for the treatment of glaucoma | ALCON, INC. (CH) | 2006-07-04 | — | — | US | disclosed |
| US-20040110791-A1 | Novel arylaminopropane analogues and their use for the treatment of glaucoma | NOVARTIS AG (CH) | 2004-06-10 | — | — | US | disclosed |
| EP-1392269-A1 | NOVEL ARYLAMINOPROPANE ANALOGUES AND THEIR USE FOR THE TREATMENT OF GLAUCOMA | Alcon, Inc. (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-6683205-B2 | FROM ARYLCARBOXYALDEHYDES OR 2-ARYL-3-HYDROXYPROPENOIC ACIDS | WISYS TECHNOLOGY FOUNDATION, INC. | 2004-01-27 | — | — | US | disclosed |
| WO-2002098400-A1 | NOVEL ARYLAMINOPROPANE ANALOGUES AND THEIR USE FOR THE TREATMENT OF GLAUCOMA | ALCON, INC. (CH) | 2002-12-12 | — | — | WO | disclosed |
| US-20020120153-A1 | Synthesis of 2-aryl propenoic acid esters for the production of non-steroidal anti-inflammatory drugs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072421-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | KLK3, AR, SHBG | ALDH1A1 1397/4885TSHR 1018/4885TTR 234/4885 |
| US-20040110791-A1 | Novel arylaminopropane analogues and their use for the treatment of glaucoma | PDE3A, PDE2A, PDE3B | ALDH1A1 750/4885TSHR 2266/4885TTR 3491/4885 |
| US-20020120153-A1 | Synthesis of 2-aryl propenoic acid esters for the production of non-steroidal anti-inflammatory drugs | ALOX15, ALOX15B, ALOX5 | ALDH1A1 253/4885TSHR 1569/4885TTR 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.