Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17205186 | 1.00 | NUDT1 (0.54) | NUDT1BACE1ELANETYMSCYP1A2 | |
| SCHEMBL18548985 | 0.82 | ELANE (0.49) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL31694921 | 0.82 | ELANE (0.49) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL31694957 | 0.79 | ELANE (0.46) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL18548984 | 0.79 | ELANE (0.46) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL18548997 | 0.79 | ELANE (0.46) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL18549020 | 0.79 | ELANE (0.46) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL31694955 | 0.79 | ELANE (0.46) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL31694934 | 0.79 | ELANE (0.46) | NUDT1BACE1ELANECYP1A2NCF1 | |
| SCHEMBL18548994 | 0.79 | ELANE (0.46) | NUDT1ELANECYP1A2ALDH1A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565586-B1 | EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES WITH POTASSIUM CHANNEL AGONISTS AND THERAPEUTIC USES THEREOF | IOVANCE BIOTHERAPEUTICS INC (US) | 2025-10-08 | — | — | EP | claimed |
| US-12629356-B2 | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof | IOVANCE BIOTHERAPEUTICS, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| EP-3565586-B1 | EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES WITH POTASSIUM CHANNEL AGONISTS AND THERAPEUTIC USES THEREOF | IOVANCE BIOTHERAPEUTICS INC (US) | 2025-10-08 | — | — | EP | disclosed |
| US-20240391880-A1 | KCa3.1 INHIBITORS FOR PODOCYTE PROTECTION | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2024-11-28 | — | — | US | disclosed |
| US-20230355540-A1 | STROKE TREATMENT | THE UNIVERSITY OF NEWCASTLE (AU) | 2023-11-09 | — | — | US | disclosed |
| CN-116617355-A | Application of LTX-315 polypeptide in preparation of antibacterial infection resisting drugs | 华中科技大学协和深圳医院 | 2023-08-22 | — | — | CN | disclosed |
| EP-4221685-A1 | STROKE TREATMENT | Oxford University Innovation Limited (GB) | 2023-08-09 | — | — | EP | disclosed |
| CN-116528843-A | Stroke treatment | 牛津大学创新有限公司 | 2023-08-01 | — | — | CN | disclosed |
| US-20230210966-A1 | EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES WITH POTASSIUM CHANNEL AGONISTS AND THERAPEUTIC USES THEREOF | LION BIOTECHNOLOGIES, INC. | 2023-07-06 | — | — | US | disclosed |
| WO-2023044315-A2 | KCA3.1 INHIBITORS FOR PODOCYTE PROTECTION | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-03-23 | — | — | WO | disclosed |
| US-11357841-B2 | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof | IOVANCE BIOTHERAPEUTICS, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| WO-2022072348-A1 | STROKE TREATMENT | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240391880-A1 | KCa3.1 INHIBITORS FOR PODOCYTE PROTECTION | PKD1, NHERF1, PKD2 | NUDT1 3607/4885BACE1 4187/4885ELANE 2786/4885 |
| US-20230210966-A1 | EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES WITH POTASSIUM CHANNEL AGONISTS AND THERAPEUTIC USES THEREOF | KCNN3, KCNK3, KCNA3 | NUDT1 2617/4885BACE1 4654/4885ELANE 2747/4885 |
| US-12629356-B2 | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof | PBK, IL2, KCNN3 | NUDT1 2879/4885BACE1 3173/4885ELANE 4828/4885 |
| US-11357841-B2 | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof | KCNN3, KCNK3, KCNA3 | NUDT1 2617/4885BACE1 4654/4885ELANE 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.