Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | THPO | P40225 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684188 | 0.86 | ADORA3 (0.48) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL26078420 | 0.86 | ADORA3 (0.48) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL26078427 | 0.86 | ADORA3 (0.48) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29684142 | 0.84 | CACNA1C (0.56) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29684265 | 0.79 | LMNA (0.59) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10830852 | 0.79 | ADORA3 (0.72) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9150273 | 0.78 | CACNA1B (0.64) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7815344 | 0.77 | ADORA3 (0.74) | ADORA3LMNAMEN1KMT2ATSHR | |
| SCHEMBL9157114 | 0.75 | MEN1 (0.70) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23686116 | 0.75 | KMT2A (0.70) | ADORA3CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022114187-A1 | COMPOUND HAVING INHIBITORY ACTION AGAINST EXCESSIVE MITOCHONDRIAL DIVISIONS | 国立大学法人九州大学 | 2022-06-02 | — | — | WO | disclosed |