Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684142 | 0.89 | CACNA1C (0.56) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7820629 | 0.85 | MAPT (0.61) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL10830852 | 0.85 | ADORA3 (0.72) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7815344 | 0.83 | ADORA3 (0.74) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL23686104 | 0.81 | KDM4E (0.69) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL23686116 | 0.81 | KMT2A (0.70) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL11862107 | 0.81 | ADORA3 (0.66) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL24469031 | 0.79 | ALDH1A1 (0.68) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL29684283 | 0.79 | ADORA3 (0.50) | LMNAKDM4EADORA3CACNA1CCACNA1F | |
| SCHEMBL7806771 | 0.79 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022114187-A1 | COMPOUND HAVING INHIBITORY ACTION AGAINST EXCESSIVE MITOCHONDRIAL DIVISIONS | 国立大学法人九州大学 | 2022-06-02 | — | — | WO | disclosed |