Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.58 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.58 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027412 | 0.88 | ADORA3 (0.89) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7806771 | 0.88 | ALDH1A1 (0.54) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20610477 | 0.85 | ADORA3 (1.00) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7820648 | 0.85 | ALDH1A1 (0.55) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL29173863 | 0.84 | ADORA3 (0.82) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL29684265 | 0.83 | LMNA (0.59) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11860075 | 0.83 | ADORA3 (0.80) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7821246 | 0.81 | RAB9A (0.51) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7817206 | 0.81 | KDM4E (0.88) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL29684142 | 0.81 | CACNA1C (0.56) | ADORA3KDM4EALDH1A1TSHRCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |