SCHEMBL29684602

SCHEMBL29684602

COc1ccc(C(O)CCc2cc(OC)c(OC)c(OC)c2)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 5/20 0.52
TUBB P07437 5/20 0.52
TUBA3C P0DPH7 5/20 0.52
TUBA1B P68363 5/20 0.52
TUBA4A P68366 5/20 0.52
TUBB4B P68371 5/20 0.52
TUBB3 Q13509 5/20 0.52
TUBB2A Q13885 5/20 0.52
TUBB8 Q3ZCM7 5/20 0.52
TUBA3E Q6PEY2 5/20 0.52
TUBA1A Q71U36 5/20 0.52
TUBA1C Q9BQE3 5/20 0.52
TUBB6 Q9BUF5 5/20 0.52
TUBB2B Q9BVA1 5/20 0.52
TUBB1 Q9H4B7 5/20 0.52
BCHE P06276 1/20 0.47
TYR P14679 1/20 0.47
ACHE P22303 1/20 0.47
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2976580 1.00 TUBB4A (0.52) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2965867 0.81 BCHE (0.49) BCHETYRACHEADRA2AADRA1A
SCHEMBL29684861 0.81 BCHE (0.49) BCHETYRACHEADRA2AADRA1A
SCHEMBL2978394 0.80 CALM1 (0.51) ADRB2
SCHEMBL30576431 0.80 AKR1B1 (0.48)
SCHEMBL1853092 0.80 AKR1B1 (0.48)
SCHEMBL2970029 0.77 STAT3 (0.57) ADRB2ADRB1
SCHEMBL29684134 0.77 STAT3 (0.57) ADRB2ADRB1
SCHEMBL2969158 0.77 ADRB2 (0.58) ADRB2
SCHEMBL29684225 0.77 ADRB2 (0.58) ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134205-B Diarylalkanes as potent inhibitors of binuclear enzymes 尤尼根公司 2022-07-19 CN disclosed