Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684225 | 1.00 | ADRB2 (0.58) | ADRB2PTPN1HTR1ATAAR1TSHR | |
| SCHEMBL29684134 | 0.92 | STAT3 (0.57) | ADRB2TSHRLMNA | |
| SCHEMBL2970029 | 0.92 | STAT3 (0.57) | ADRB2TSHRLMNA | |
| SCHEMBL2978394 | 0.83 | CALM1 (0.51) | ADRB2 | |
| SCHEMBL28050423 | 0.83 | PTPN1 (0.51) | ADRB2PTPN1HTR1ATAAR1TSHR | |
| SCHEMBL29684623 | 0.83 | ALOX15 (0.50) | ADRB2HTR1ATAAR1TSHRMAPK1 | |
| SCHEMBL2977752 | 0.83 | ALOX15 (0.50) | ADRB2HTR1ATAAR1TSHRMAPK1 | |
| SCHEMBL2975079 | 0.81 | TTR (0.50) | ADRB2TAAR1 | |
| SCHEMBL1853092 | 0.81 | AKR1B1 (0.48) | PTPN1 | |
| SCHEMBL30576431 | 0.81 | AKR1B1 (0.48) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2021-03-25 | — | — | US | claimed |
| US-20200170907-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2020-06-04 | — | — | US | claimed |
| US-20160193126-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN INC (US) | 2016-07-07 | — | — | US | claimed |
| EP-1748767-A4 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS INC (US) | 2008-12-24 | — | — | EP | claimed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | claimed |
| EP-1748767-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | Unigen Pharmaceuticals, Inc. (US) | 2007-02-07 | — | — | EP | claimed |
| WO-2005117849-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | claimed |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | US | claimed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-10857082-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2020-12-08 | — | — | US | disclosed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| EP-1748767-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | Unigen Pharmaceuticals, Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005117849-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200170907-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | ADRB2 2316/4885PTPN1 1357/4885HTR1A 2899/4885 |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | ADRB2 2316/4885PTPN1 1357/4885HTR1A 2899/4885 |
| US-20160193126-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | ADRB2 2316/4885PTPN1 1357/4885HTR1A 2899/4885 |
| US-10857082-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | ADRB2 2316/4885PTPN1 1357/4885HTR1A 2899/4885 |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | ADRB2 2316/4885PTPN1 1357/4885HTR1A 2899/4885 |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | TYR, MAOA, CYP51A1 | ADRB2 3586/4885PTPN1 3131/4885HTR1A 1154/4885 |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | ADRB2 2316/4885PTPN1 1357/4885HTR1A 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.