Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 3/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135449 | 1.00 | CRBN (0.37) | CRBNSMOADAMTS5ADAM17MMP2 | |
| SCHEMBL20135450 | 1.00 | CRBN (0.37) | CRBNSMOADAMTS5ADAM17MMP2 | |
| SCHEMBL20135547 | 0.84 | KDM4E (0.37) | CRBNADAMTS5ADAM17MMP2MEN1 | |
| SCHEMBL20134817 | 0.84 | ALDH1A1 (0.37) | CRBNADAMTS5ADAM17MMP2MEN1 | |
| SCHEMBL29689068 | 0.84 | KDM4E (0.37) | CRBNADAMTS5ADAM17MMP2MEN1 | |
| SCHEMBL29688621 | 0.84 | ALDH1A1 (0.37) | CRBNADAMTS5ADAM17MMP2MEN1 | |
| SCHEMBL20135628 | 0.83 | ADAMTS5 (0.42) | CRBNADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL20135626 | 0.83 | ADAMTS5 (0.42) | CRBNADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL29689188 | 0.83 | ADAMTS5 (0.42) | CRBNADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL20134860 | 0.82 | SLC6A7 (0.43) | ADAMTS5ADAM17MEN1KMT2ASLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |