SCHEMBL2968841

SCHEMBL2968841

NC(=S)n1nnc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 1/20 0.61
▸ MGAM O43451 9/20 0.54
▸ AMY1A P0DUB6 9/20 0.54
▸ GAA P10253 9/20 0.54
▸ SI P14410 9/20 0.54
▸ MGAM2 Q2M2H8 9/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ SLC9A1 P19634 2/20 0.54
▸ F2 P00734 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ ALDH1A1 P00352 2/20 0.52
▸ MAPT P10636 2/20 0.52
▸ POLB P06746 1/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ ATM Q13315 1/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ CYP2D6 P10635 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ THPO P40225 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2970279 0.84 DGAT1 (0.66) DGAT1MGAMAMY1AGAASI
SCHEMBL28300681 0.82 DGAT1 (0.63) DGAT1MGAMAMY1AGAASI
SCHEMBL1520814 0.81 DGAT1 (0.72) DGAT1MGAMAMY1AGAASI
SCHEMBL29163194 0.81 DGAT1 (0.61) DGAT1MGAMAMY1AGAASI
SCHEMBL443991 0.81 GAA (0.64) DGAT1MGAMAMY1AGAASI
SCHEMBL27973795 0.79 DGAT1 (0.70) DGAT1MGAMAMY1AGAASI
Hydrochloric Acid SCHEMBL2681010 0.79 DGAT1 (0.70) DGAT1MGAMAMY1AGAASI
SCHEMBL13604213 0.77 DGAT1 (0.56) DGAT1MGAMAMY1AGAASI
SCHEMBL4250719 0.76 GAA (0.68) DGAT1MGAMAMY1AGAASI
SCHEMBL706083 0.76 MGAM (0.68) DGAT1MGAMAMY1AGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230261203-A1 LITHIUM SECONDARY BATTERY TERAWATT TECHNOLOGY K.K. (JP) 2023-08-17 — — US disclosed
WO-2020197963-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2020-10-01 — — WO disclosed
EP-1973887-B1 AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS IMMUPHARMA FRANCE SA (FR) 2012-09-19 — — EP disclosed
EP-1973887-B1 AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS IMMUPHARMA FRANCE SA (FR) 2012-09-19 — — EP disclosed
US-20100291199-A1 Compositions and Methods For The Treatment and Prevention of Disease CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-11-18 — — US disclosed
US-7777030-B2 Compositions and methods for the treatment and prevention of disease Centre National de la Recherge Scientifique (CNRS) (FR) 2010-08-17 — — US disclosed
CN-101405276-A Compositions and methods for the inhibition of phospholipase A2 IMMUPHARMA FRANCE SA (FR) 2009-04-08 — — CN disclosed
CN-101400352-A Compositions and methods for the treatment and prevention of disease IMMUPHARMA FRANCE SA (FR) 2009-04-01 — — CN disclosed
CN-101395143-A Aza heterocyclics for the treatment of malaria or aids IMMUPHARMA FRANCE SA (FR) 2009-03-25 — — CN disclosed
EP-1973887-A1 AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS Immupharma France SA (FR) 2008-10-01 — — EP disclosed
EP-1965806-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF DISEASE IMMUPHARMA FRANCE SA (FR) 2008-09-10 — — EP disclosed
US-20080033167-A1 Compositions and methods for synthesizing heterocyclic therapeutic compounds UREKA SARL (FR) 2008-02-07 — — US disclosed
US-20080031951-A1 Compositions and methods for the inhibition of phospholipase A2 IMMUPHARMA FRANCE SA (FR) 2008-02-07 — — US disclosed
US-20070293469-A1 Compositions and methods for the treatment and prevention of disease UREKA SARL (FR) 2007-12-20 — — US disclosed
WO-2007074169-A2 COMPOSITIONS AND METHODS FOR THE INHIBITION OF PHOSPHOLIPASE A2 IMMUPHARMA FRANCE SA (FR) 2007-07-05 — — WO disclosed
WO-2007074169-A2 COMPOSITIONS AND METHODS FOR THE INHIBITION OF PHOSPHOLIPASE A2 IMMUPHARMA FRANCE SA (FR) 2007-07-05 — — WO disclosed
WO-2007074170-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF DISEASE IMMUPHARMA FRANCE SA (FR) 2007-07-05 — — WO disclosed
WO-2007074170-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF DISEASE IMMUPHARMA FRANCE SA (FR) 2007-07-05 — — WO disclosed
WO-2007074171-A1 AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS IMMUPHARMA FRANCE SA (FR) 2007-07-05 — — WO disclosed
WO-2007074171-A1 AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS IMMUPHARMA FRANCE SA (FR) 2007-07-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100291199-A1 Compositions and Methods For The Treatment and Prevention of Disease DNPEP, VIP, PEPD DGAT1 3347/4885MGAM 2735/4885AMY1A 2521/4885
US-20080031951-A1 Compositions and methods for the inhibition of phospholipase A2 PLA2G1B, PLA2G4A, PLA2G12A DGAT1 535/4885MGAM 2238/4885AMY1A 1315/4885
US-20070293469-A1 Compositions and methods for the treatment and prevention of disease DNPEP, VIP, PEPD DGAT1 3347/4885MGAM 2735/4885AMY1A 2521/4885
US-20080033167-A1 Compositions and methods for synthesizing heterocyclic therapeutic compounds DNPEP, VIP, NGLY1 DGAT1 3177/4885MGAM 2584/4885AMY1A 4682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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