SCHEMBL29695576

SCHEMBL29695576

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nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ENPEP Q07075 5/20 0.42
▸ BACE1 P56817 8/20 0.41
▸ BACE2 Q9Y5Z0 2/20 0.41
▸ CTSD P07339 2/20 0.41
▸ KEAP1 Q14145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29695562 0.92 BACE1 (0.45) ENPEPBACE1BACE2CTSD
SCHEMBL29352968 0.88 FOLH1 (0.41) —
SCHEMBL31332141 0.88 FOLH1 (0.41) —
SCHEMBL31031450 0.87 FURIN (0.48) BACE1BACE2CTSD
SCHEMBL29695558 0.87 BACE1 (0.43) BACE1BACE2CTSD
SCHEMBL29351135 0.86 GNPAT (0.45) ENPEPBACE1KEAP1
SCHEMBL31400977 0.85 NMT1 (0.47) BACE1BACE2CTSD
SCHEMBL29370769 0.84 ENPEP (0.46) ENPEPBACE1BACE2CTSD
SCHEMBL6856783 0.84 NMT2 (0.46) BACE1
SCHEMBL6856774 0.84 NMT2 (0.46) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267193-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF Ludwig-Maximilians-Universität München (DE) 2023-11-01 — — EP disclosed
WO-2022136555-A9 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-09-22 — — WO disclosed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 — — WO disclosed
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF TUBB6, GALNT10, TUBB ENPEP 153/4885BACE1 2881/4885BACE2 2246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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