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SCHEMBL29695624

SCHEMBL29695624

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nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.59
▸ OPRD1 P41143 8/20 0.57
▸ OPRM1 P35372 7/20 0.57
▸ OPRK1 P41145 1/20 0.54
▸ CALCRL Q16602 4/20 0.53
▸ REN P00797 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29856042 0.90 RAMP3 (0.56) SLC6A2OPRD1OPRM1
SCHEMBL30906513 0.88 RAMP3 (0.55) OPRD1OPRM1
SCHEMBL29398783 0.87 OPRM1 (0.57) SLC6A2OPRD1OPRM1OPRK1CALCRL
SCHEMBL30726587 0.86 RAMP3 (0.61) OPRD1OPRM1
SCHEMBL32681292 0.86 SLC6A2 (0.63) SLC6A2OPRD1OPRM1REN
SCHEMBL31000918 0.86 RAMP3 (0.58) OPRD1OPRM1
SCHEMBL11650974 0.86 OPRD1 (0.62) OPRD1OPRM1OPRK1
SCHEMBL31388233 0.86 KEAP1 (0.60) SLC6A2OPRD1OPRM1
SCHEMBL30906353 0.85 CALCR (0.59) —
SCHEMBL30607280 0.85 CALCR (0.59) OPRD1OPRM1OPRK1CALCRL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267193-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF Ludwig-Maximilians-Universität München (DE) 2023-11-01 — — EP disclosed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 — — WO disclosed
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