SCHEMBL29696201

SCHEMBL29696201

CCCC(=O)Nc1ccc(-c2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.73
ALDH1A1 P00352 3/20 0.58
HPGD P15428 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
LMNA P02545 1/20 0.58
CYP3A4 P08684 2/20 0.58
MAPT P10636 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C19 P33261 1/20 0.52
ESRRA P11474 1/20 0.51
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29696224 0.91 TP53 (0.59) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL29696197 0.90 TP53 (0.58) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL3674141 0.87 CYP3A4 (0.75) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL3102003 0.80 KMT2A (0.57) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL17405142 0.79 TP53 (0.86) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL8278746 0.79 TP53 (0.72) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL4727600 0.78 ALDH1A1 (0.52) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL28850547 0.78 TP53 (0.83) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL8813883 0.78 TP53 (0.83) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL1876366 0.77 L3MBTL1 (0.69) ALDH1A1HPGDMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022139564-A1 NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME (주)앰틱스바이오 2022-06-30 WO disclosed