Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727599 | 0.85 | ALDH1A1 (0.67) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4726842 | 0.83 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4727645 | 0.82 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4779788 | 0.79 | SMN1; SMN2 (0.57) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4781491 | 0.78 | NPC1 (0.50) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4726932 | 0.78 | RAB9A (0.64) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL29696201 | 0.78 | TP53 (0.73) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3674141 | 0.75 | CYP3A4 (0.75) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL2128024 | 0.74 | RAB9A (0.66) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4842127 | 0.73 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |