Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925555 | 1.00 | FLT1 (0.34) | FLT1KDRFLT4FLT3PRKAB2 | |
| SCHEMBL28733699 | 0.87 | VCP (0.33) | FLT1KDRFLT4FLT3PRKAB2 | |
| SCHEMBL22925775 | 0.87 | VCP (0.33) | FLT1KDRFLT4FLT3PRKAB2 | |
| SCHEMBL22925928 | 0.84 | KMT2A (0.40) | FLT1KDRFLT4FLT3VCP | |
| SCHEMBL28733637 | 0.84 | KMT2A (0.40) | FLT1KDRFLT4FLT3VCP | |
| SCHEMBL24636935 | 0.84 | FLT1 (0.41) | FLT1KDRFLT4FLT3PRKAB2 | |
| SCHEMBL22925817 | 0.84 | FLT1 (0.41) | FLT1KDRFLT4FLT3PRKAB2 | |
| SCHEMBL29696293 | 0.84 | FLT1 (0.41) | FLT1KDRFLT4FLT3PRKAB2 | |
| SCHEMBL22925740 | 0.82 | ALOX5 (0.39) | FLT1KDRFLT4FLT3PRKAB2 | |
| SCHEMBL22925766 | 0.82 | ALOX5 (0.39) | FLT1KDRFLT4FLT3PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448371-B2 | Inhibitor compounds | Cincera Therapeutics Pty Ltd (AU) | 2025-10-21 | — | — | US | claimed |
| US-20260001870-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2026-01-01 | — | — | US | disclosed |
| US-12448371-B2 | Inhibitor compounds | Cincera Therapeutics Pty Ltd (AU) | 2025-10-21 | — | — | US | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001870-A1 | INHIBITOR COMPOUNDS | CES1, NCEH1, NR1H2 | FLT1 2182/4885KDR 3311/4885FLT4 3558/4885 |
| US-12448371-B2 | Inhibitor compounds | SERPINB1, MMP1, SSB | FLT1 2567/4885KDR 3951/4885FLT4 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.