Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868513 | 1.00 | APLNR (0.42) | APLNRMIFGABRPGABRDGABRA1 | |
| SCHEMBL14058771 | 0.74 | PLAU (0.56) | APLNRMIFGABRPGABRDGABRA1 | |
| SCHEMBL23804264 | 0.73 | APLNR (0.39) | APLNRMIFGABRPGABRDGABRA1 | |
| SCHEMBL4059428 | 0.73 | MAPK1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20862044 | 0.73 | NAAA (0.48) | MIFNAAA | |
| SCHEMBL4474826 | 0.73 | CYP19A1 (0.50) | CA12CA1CA2CA9MAPT | |
| SCHEMBL6902852 | 0.72 | ADRA2A (0.50) | APLNRMIFGABRPGABRDGABRA1 | |
| SCHEMBL5801527 | 0.72 | ADRA2A (0.50) | APLNRMIFGABRPGABRDGABRA1 | |
| SCHEMBL32681547 | 0.72 | MIF (0.45) | MIF | |
| SCHEMBL557613 | 0.72 | PDGFRB (0.48) | MAPTHPGDSEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |