SCHEMBL557613

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL558034	0.81	NQO2 (0.42)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL27796937	0.75	PDE10A (0.42)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL558472	0.75	NQO2 (0.42)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL14970152	0.74	ALDH1A1 (0.56)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL23651807	0.72	ALDH1A1 (0.55)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL6844994	0.72	NCF1 (0.59)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL14058771	0.72	PLAU (0.56)	RAB9AKDM4ENPC1LMNA
	SCHEMBL621383	0.72	ALDH1A1 (0.55)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL559347	0.72	ALDH1A1 (0.55)	PDGFRBPDGFRAALDH1A1RAB9AMEN1
	SCHEMBL29696296	0.72	APLNR (0.42)	HPGDSEGFRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.