Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 19/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21741484 | 0.94 | GPR84 (0.66) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL297566 | 0.91 | GPR84 (0.77) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL297729 | 0.91 | GPR84 (0.81) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL3922363 | 0.90 | GPR84 (0.72) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL21741485 | 0.88 | GPR84 (0.62) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL887435 | 0.88 | GPR84 (0.80) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL887269 | 0.86 | GPR84 (0.74) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL296149 | 0.86 | GPR84 (0.82) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL25484963 | 0.85 | GPR84 (0.75) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL887278 | 0.85 | GPR84 (1.00) | GPR84MEN1KMT2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667733-B2 | Polyvinyl esters and methods related thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667733-B2 | Polyvinyl esters and methods related thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-06 | — | — | US | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210324121-A1 | POLYVINYL ESTERS AND METHODS RELATED THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2021-10-21 | — | — | US | disclosed |
| US-20200234798-A1 | EXTRAPOLATIVE PREDICTION OF ENANTIOSELECTIVITY ENABLED BY COMPUTER-DRIVEN WORKFLOW, NEW MOLECULAR REPRESENTATIONS AND MACHINE LEARNING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-07-23 | — | — | US | disclosed |
| WO-2020037163-A1 | POLYVINYL ETHERS AND METHODS RELATED THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2020-02-20 | — | — | WO | disclosed |
| US-8350040-B2 | Process for preparing (alpha S, beta R)-6-bromo-alpha-[2-(dimethylamino)ethyl]-2- methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinolineethanol | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-01-08 | — | — | US | disclosed |
| EP-1888604-B1 | PROCESS FOR PREPARING (ALPHA S, BETA R)-6-BROMO-ALPHA-[2-(DIMETHYLAMINO)ETHYL]-2-METHOXY-ALPHA-1-NAPHTHALENYL-BETA-PHENYL-3-QUINOLINEETHANOL | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-14 | — | — | EP | disclosed |
| US-20110319623-A1 | PROCESS FOR PREPARING (ALPHA S, BETA R)-6-BROMO-ALPHA-[2-(DIMETHYLAMINO)ETHYL]-2-METHOXY-ALPHA-1-NAPHTHALENYL-BETA-PHENYL-3-QUINOLINEETHANOL | CILAG AG (CH) | 2011-12-29 | — | — | US | disclosed |
| US-8039628-B2 | Isolation from mixture of stereoisomers; optical resolution of enantiomorphs | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-10-18 | — | — | US | disclosed |
| US-7683191-B2 | Organic salts and method for producing chiral organic compounds | Studiangesellschaft Kohle mbH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-7683191-B2 | Organic salts and method for producing chiral organic compounds | Studiangesellschaft Kohle mbH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-7517828-B2 | Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| US-20080200683-A1 | Process for Preparing (Alpha S, Beta R)-6-Bromo-Alpha-[2-(Dimethylamino) Ethyl]-2-Methoxy-Alpha-1-Naphthalenyl-Beta-Phenyl-3-Quinolineethanol | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-21 | — | — | US | disclosed |
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1623971-A1 | ASYMMETRIC-SYNTHESIS CATALYST BASED ON CHIRAL BROENSTED ACID AND METHOD OF ASYMMETRIC SYNTHESIS WITH THE CATALYST | TOAGOSEI CO., LTD. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | ICMT, OTC, PNPO | GPR84 3716/4885MEN1 2400/4885KMT2A 2501/4885 |
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | LSS, COASY, FASN | GPR84 2758/4885MEN1 169/4885KMT2A 2039/4885 |
| US-20080200683-A1 | Process for Preparing (Alpha S, Beta R)-6-Bromo-Alpha-[2-(Dimethylamino) Ethyl]-2-Methoxy-Alpha-1-Naphthalenyl-Beta-Phenyl-3-Quinolineethanol | LBR, ADRA1A, ADRA1D | GPR84 1474/4885MEN1 1168/4885KMT2A 1760/4885 |
| US-20110319623-A1 | PROCESS FOR PREPARING (ALPHA S, BETA R)-6-BROMO-ALPHA-[2-(DIMETHYLAMINO)ETHYL]-2-METHOXY-ALPHA-1-NAPHTHALENYL-BETA-PHENYL-3-QUINOLINEETHANOL | LBR, ADRA1A, ADRA1D | GPR84 1474/4885MEN1 1168/4885KMT2A 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.