Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15174381 | 0.81 | ERN1 (0.50) | ERN1PIM1MAPTCYP11B1CYP11B2 | |
| SCHEMBL22652108 | 0.78 | ERN1 (0.52) | ERN1PIM1MAPTPIM2CDK2 | |
| SCHEMBL2810982 | 0.76 | LDHA (0.54) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16134054 | 0.75 | MAPT (0.58) | ERN1PIM1MAPTALDH1A1PIM2 | |
| SCHEMBL21408174 | 0.75 | TGFBR1 (0.46) | ERN1PIM1MAPTPIM3PIM2 | |
| SCHEMBL545037 | 0.74 | ACVR1B (0.47) | ERN1PIM1MAPTPIM3PIM2 | |
| SCHEMBL29061506 | 0.74 | PIM1 (0.51) | PIM1MAPTCYP11B1CYP11B2IRAK4 | |
| SCHEMBL27775498 | 0.74 | ALDH1A1 (0.42) | ERN1MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14689223 | 0.72 | CYP2A6 (0.53) | PIM1MAPTCYP2C9CYP2C19CYP11B1 | |
| SCHEMBL17680436 | 0.72 | ERN1 (0.46) | ERN1MAPTALDH1A1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124554-B | Pyrrolopyrimidine compound, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-116685323-A | Purinone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-115124554-A | Pyrrolopyrimidine compound, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022135360-A1 | PURINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-06-30 | — | — | WO | disclosed |