Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416805 | 0.86 | ALDH1A1 (0.48) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL1417187 | 0.86 | CYP1A2 (0.38) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL20286381 | 0.86 | RAB9A (0.52) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL789255 | 0.86 | CYP1A2 (0.38) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL8378803 | 0.86 | CHRM4 (0.50) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28753858 | 0.84 | LOXL2 (0.40) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL1417155 | 0.84 | MAPT (0.37) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL2969884 | 0.84 | MAPT (0.37) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL27613451 | 0.81 | MAPT (0.36) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL1416919 | 0.81 | ADRB2 (0.44) | CYP1A2CYP19A1CYP2C9CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |