Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 13/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17593575 | 0.81 | USP2 (0.38) | USP2ALDH1A1HSD17B10CYP1A2MAPK1 | |
| Fluoride SCHEMBL27569822 | 0.79 | MEN1 (0.56) | USP2ALDH1A1HSD17B10CYP1A2MAPK1 | |
| Biphenyl SCHEMBL19717525 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CYP1A2MAPK1CYP3A4 | |
| SCHEMBL28792803 | 0.77 | HTR7 (0.43) | USP2ALDH1A1HSD17B10CYP1A2MAPK1 | |
| SCHEMBL6561470 | 0.77 | CHKA (0.59) | USP2ALDH1A1HSD17B10CYP1A2MAPK1 | |
| SCHEMBL24093710 | 0.76 | LTA4H (0.44) | USP2ALDH1A1MAPK1CYP2D6TP53 | |
| SCHEMBL16400663 | 0.76 | KDM4E (0.53) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2692445 | 0.76 | MAPT (0.59) | USP2ALDH1A1HSD17B10MAPK1CYP2C19 | |
| SCHEMBL21957634 | 0.76 | HDAC4 (0.54) | USP2ALDH1A1CYP1A2MAPK1CYP2C19 | |
| SCHEMBL22816129 | 0.76 | AKR1C3 (0.42) | USP2ALDH1A1MAPK1CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230088214-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230089374-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230079913-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-16 | — | — | US | disclosed |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079913-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | USP2 1874/4885ALDH1A1 481/4885HSD17B10 296/4885 |
| US-20230088214-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | USP2 1929/4885ALDH1A1 552/4885HSD17B10 281/4885 |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | XDH, PNPO, AGXT | USP2 1874/4885ALDH1A1 481/4885HSD17B10 296/4885 |
| US-20230089374-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | USP2 1874/4885ALDH1A1 481/4885HSD17B10 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.