SCHEMBL1930872

SCHEMBL1930872

O=C1CC(OCc2ccccc2)C(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 4/20 0.41
PSEN2 P49810 4/20 0.41
APH1B Q8WW43 4/20 0.41
NCSTN Q92542 4/20 0.41
APH1A Q96BI3 4/20 0.41
PSENEN Q9NZ42 4/20 0.41
MAPT P10636 1/20 0.40
CYP2C19 P33261 1/20 0.40
CTSL P07711 2/20 0.40
CTSB P07858 2/20 0.40
CTSK P43235 2/20 0.40
CTSV O60911 1/20 0.40
CTSS P25774 1/20 0.40
CTSC P53634 1/20 0.40
CTSF Q9UBX1 1/20 0.40
PDPK1 O15530 1/20 0.38
MTOR P42345 1/20 0.38
AKT1 P31749 1/20 0.38
CYP1A2 P05177 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28660105 1.00 PSEN1 (0.41) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8792320 0.81 KLK5 (0.39) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL23047657 0.79 CTRC (0.38) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15095433 0.74 LMNA (0.48) MAPTCYP2C19AKT1LMNATSHR
SCHEMBL15095406 0.74 LMNA (0.48) MAPTCYP2C19AKT1LMNATSHR
SCHEMBL1930873 0.74 DDB1 (0.44) CTSLCTSBCTSKCTSVCTSS
SCHEMBL29015434 0.73 CYP1A2 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL24190480 0.73 CYP1A2 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL19028117 0.73 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL10735399 0.73 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363662-A1 COMPOSITIONS AND METHODS FOR MAKING PAPER USING UNCOOKED STARCH FOR GYPSUM PANELS Knauf Gips KG (DE) 2024-05-08 EP disclosed
US-20230002974-A1 COMPOSITIONS AND METHODS FOR MAKING PAPER USING UNCOOKED STARCH FOR GYPSUM PANELS KNAUF GIPS KG (DE) 2023-01-05 US disclosed
WO-2023275852-A1 COMPOSITIONS AND METHODS FOR MAKING PAPER USING UNCOOKED STARCH FOR GYPSUM PANELS KNAUF GIPS KG (DE) 2023-01-05 WO disclosed
CN-113813388-B Nano micelle for eyes and preparation method and application thereof 浙江大学 2022-09-09 CN disclosed
CN-113813388-A Nano micelle for eyes and preparation method and application thereof 浙江大学 2021-12-21 CN disclosed
US-10774473-B2 Compositions and methods with microfibrillated cellulose for wallboard paper UNITED STATES GYPSUM COMPANY (US) 2020-09-15 US disclosed
EP-3631084-A1 COMPOSITIONS AND METHODS WITH MICROFIBRILLATED CELLULOSE FOR WALLBOARD PAPER United States Gypsum Company (US) 2020-04-08 EP disclosed
CN-110651083-A Composition and method for wallboard paper with microfibrillated cellulose 美国石膏公司 2020-01-03 CN disclosed
US-20180340297-A1 COMPOSITIONS AND METHODS WITH MICROFIBRILLATED CELLULOSE FOR WALLBOARD PAPER UNITED STATES GYPSUM COMPANY 2018-11-29 US disclosed
US-8506945-B2 Polymers with structure-defined functions SMITH & NEPHEW, PLC. (GB) 2013-08-13 US disclosed
US-20110300096-A1 Polymers With Structure-Defined Functions GREENER BRYAN (GB) 2011-12-08 US disclosed
US-7955594-B2 Maleic anhydride-methyl vinyl ether copolymers; polyamic acids; medical implant device, dressing, scaffold, or fluid adhesive for treatment or prophylaxis of wounds; enhanced activity of protease inhibitors and neurotransmitter drugs SMITH & NEPHEW, PLC (GB) 2011-06-07 US disclosed
US-20050032929-A1 Polymers with structure-defined functions SMITH & NEPHEW, PLC (GB) 2005-02-10 US disclosed
EP-1436334-A1 POLYMERS WITH STRUCTURE-DEFINED FUNCTIONS Smith & Nephew PLC (GB) 2004-07-14 EP disclosed
WO-2003027154-A1 POLYMERS WITH STRUCTURE-DEFINED FUNCTIONS SMITH & NEPHEW PLC (GB) 2003-04-03 WO disclosed
US-4853085-A Neutral sized paper for use in the production of gypsum wallboard UNITED STATES GYPSUM COMPANY (US) 1989-08-01 US disclosed
US-4548676-A IMPROVED POROSITY UNITED STATES GYPSUM COMPANY (US) 1985-10-22 US disclosed
US-4470877-A SIZING CELLULOSE FIBERS, ANIONIC POLYMERS UNITED STATES GYPSUM COMPANY (US) 1984-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110300096-A1 Polymers With Structure-Defined Functions MMP1, MMP8, ADAM12 PSEN1 1287/4885PSEN2 1901/4885APH1B 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.