Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.58 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954751 | 0.85 | ALDH1A1 (0.67) | ACHEALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL281572 | 0.85 | TGM2 (0.57) | ACHEALDH1A1ALDH3A1ALDH2CES1 | |
| SCHEMBL5657440 | 0.80 | ALDH1A1 (0.67) | ACHEALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL28469805 | 0.80 | ACHE (0.70) | ACHEALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL28799626 | 0.80 | ALDH1A1 (0.62) | ACHEALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL5659567 | 0.78 | ALDH1A1 (0.71) | ACHEALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL18954567 | 0.77 | ALDH1A1 (0.55) | ACHEALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL18955277 | 0.75 | PARK7 (0.63) | ALDH1A1ALDH3A1CHRM5TP53MAPT | |
| SCHEMBL5659265 | 0.74 | ALDH1A1 (1.00) | ACHEALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL18954858 | 0.73 | ACHE (0.63) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747883-B | 1-benzyl isatin derivative and synthesis method and application thereof | 中南大学 | 2022-07-01 | — | — | CN | disclosed |