Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26185623 | 1.00 | CA12 (0.50) | CA12CA1CA2CA6CA9 | |
| SCHEMBL11653117 | 0.86 | CA12 (0.48) | CA12CA1CA2CA6CA9 | |
| SCHEMBL29503148 | 0.82 | PARP1 (0.55) | HSD17B10MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL563489 | 0.82 | CA2 (0.52) | CA12CA1CA2CA6CA9 | |
| SCHEMBL562694 | 0.82 | CA2 (0.54) | CA12CA1CA2CA6CA9 | |
| SCHEMBL30223402 | 0.81 | HDAC8 (0.59) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30223420 | 0.81 | HDAC8 (0.59) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15177798 | 0.80 | KMO (0.57) | CA12CA1CA2CA6CA9 | |
| SCHEMBL24478812 | 0.79 | RAB9A (0.53) | CA12CA1CA2CA9HPGD | |
| SCHEMBL31317830 | 0.79 | RAB9A (0.53) | CA12CA1CA2CA9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011633-A1 | ANTAGONIST OF MAS-RELATED G PROTEIN-COUPLED RECEPTOR X2 AND USE THEREOF | 北京普祺医药科技股份有限公司 | 2025-01-16 | — | — | WO | disclosed |
| EP-4251615-A1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022112188-A1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-02 | — | — | WO | disclosed |